Supplemental Data NF-κB, IκB, and IRAK Control Glutamate Receptor Density at the Drosophila NMJ
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NF-κB, IκB, and IRAK Control Glutamate Receptor Density at the Drosophila NMJ
NF-kB signaling has been implicated in neurodegenerative disease, epilepsy, and neuronal plasticity. However, the cellular and molecular activity of NF-kB signaling within the nervous system remains to be clearly defined. Here, we show that the NF-kB and IkB homologs Dorsal and Cactus surround postsynaptic glutamate receptor (GluR) clusters at the Drosophila NMJ. We then show that mutations in ...
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